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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '22e0adc6bc55559aab63c201857b4edb9f724ce1f1b0d05ed88620329a793ae7' 
  AND token = 'VbXxY4fpjAWg8bQZZkXVUcZRo7u/jCbeUuSFOxbBIio=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}