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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2250bdd4d0369bd3fa763d79f806b569ff4936496f661c6a13505bc5a6cb6344' 
  AND token = 'gQQUnwevW6kJW8+KklNZ9H3zTPtRKPQjjlFA2ut70h4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}