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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c594be398c4df3d5a8c8c7a945527e4226c04e8a8d114eeb1cda1d6d337732ec' 
  AND token = '/y/To86u8NxxxjZa4waonvh+oDx+0gg00krG+9KZPsE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}