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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '39e4a3186f3fcf16f9c399e5a7cea456bc2292ea8b18ae4e9e5f2670b91dda8b' 
  AND token = 'g5gGIRdbUA1Y4o++4NPaK7lRZnJFPAGi0hWiT71Se20=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}