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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1a8a6e10826ba86131955ab88790fdc8fdd90e5c52f55f2ceb132b0632151242' 
  AND token = 'ARelO/RldtHE/D0NWm4L2TZ2VRRWrwM6+25MiTcAQPA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}