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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9622198596acdc4e35e4a4cd41718c9a59bb38dc08267f8d4044aa836a2b9926' 
  AND token = 'tzhoUJ20lG00VZVH2yrc+qwUl0SPFpl8rgSDEjC76VA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}