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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8ed2ae259463117d1ed284fdf41ff53f814e2a99f973a561896ed9da19973a84' 
  AND token = 'CQ4C4g6a9nfYKwaDd4b8urXoXHDHSEpp/MXcRUT1Kao=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}