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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd5235cafad77f6d1144c9ec2a55ba9a709da5e8322e4a04bc47d6d867c2af909' 
  AND token = 'cgnDAi4Q8AJNIEEGm3KZ3KQBqQgxOnukpfn7j9FHWzc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}