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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b0c40d2b2359db8890bdf954ac9876ba6232eee279e05af46b334b029c5bda82' 
  AND token = 'Wc4pJxk3ZV1SuENWHVRDMFRkEobqvrPsIy2KynzC7qE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}