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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3321d609de8a09a20c3a8775aceb08a72d2d2d0a9b1c020ef0abb1d67c898706' 
  AND token = 'X6A6hnrpkf1j9zy4BaFG//7KCIX7QbFVciph0y58WIk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}