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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '42b31d025ed6d2b2fc3f23ba9d2527107676f073e84c59e7ab40d9bc891a5f6e' 
  AND token = 'Ku2OouGz3Nb2Hxkld/lr65aVFd7i8rbJhvdpKRbO3qY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}