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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a035f5537e37b53d928093285358a71cd16ab4b54c1bc795f3e433d45e3bce41' 
  AND token = 'JxeCb42b3lAKvKUJ7lRXmAKkHgCrVrf0O88xa2cMYj8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}