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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a150f5291a8644d9f7188d36ec1868b6c3d9fd5eade97d38de49da29731685b9' 
  AND token = 'tpD5rtCv2JJ0T07MtiYE7l/w0oDBm3daVjao67OmLc4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}