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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ad55ac3ad3ed1c48c59eb1b65349beab129874088aa70750895cd9c878da8c26' 
  AND token = 'pQojVcKXF/sw7vDn/13i7I98CwRSc97m9BRd4GkUpVQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}