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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ad60c61fb92ecde460fff7db4942cae960bd28bc1787e09c9cb222da7077904b' 
  AND token = 'i8+78T3upmx6+YNtlhRer+ctyuu1T9PyiqottctlS24=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}