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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'deb01889c5e3f9cfe227c0885247a79f1c1ff305cd3e47064dee17585f3972cd' 
  AND token = 'ZAxLle9GdTA0lZqsaZGEAHL14TrbF+FoG7zcRLYsfCg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00121

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}