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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9a1e456c64b98d3a2b40ce3cffc7ad22ecdf6b43473dc18ee68c06f48b55fc83' 
  AND token = 'ez7k0FSNMfS+G6l9fmURPbYuxPIRiOj9zZzbG5XFmaw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}