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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c597a051ac3bee9d28ad5f25c76d77de12679166bbb782ae01c0670db0f1b5f7' 
  AND token = 'QA+7/WP0rLCLmqU8C/KFRe7hiF3RRbq8ABDNkRwDDho=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}