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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c73b383bbaaba20b96ab9d6f689d24c58553a405236ce037423cdf21e271db8c' 
  AND token = 'bXszzOhW/Ia1UMXpfqHmVboSCZMvGXKEdfcEamKsn2U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00055

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}