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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7bc56bdf9cf629a3489dd527b46c436a33239fd270ab8fa10b1b49a9cd68c5f1' 
  AND token = 'siwmkBgWkziQa/HLNFg5hcdSMQRD33ekSoSVf2Y8zS4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}