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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1b15bd79aeb68f4bdba93229dc0109d464b8915a2ac5af8e8848d855f9f08371' 
  AND token = 'fz4QPLenKq/yscD4dbIQzCrmk6zI4/1W2ZsKZlWFyLo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}