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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c8fcbcaaad881398539cde3bb5a7c1850d1f3741de237b1c9d905e26c27ec4e0' 
  AND token = '04Uf6IlBv25rO/fWf/Q9lzvJOBbd7nWrVShIh4ixNUw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}