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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8a9f458dfab06e0eaa206734d0320167fa1b6bad2ee722709fedb144fc426a1c' 
  AND token = 'P4XZGTIzo4tD5Ws3dXn9bh4Xfz9FLpJiNaU2tk5Eyns=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}