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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b1a015248f58f3f765ca0b7ff1bc1b8304905143b4219032a0fe6baaac897a42' 
  AND token = 's4L9YVOPMaXmYe6oZxFz1ikXOCSYZzINenLeZbdLURE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}