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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd9ab723133baa0da026813a837cdefaa2cb36b74073e655ede86c2648822a3fe' 
  AND token = 'GEk+7da1Ii7r0TBPRnk2EWsKERNMZq9jyiHT1nsmDJQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}