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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd968431c0f3c78807f84341df784e8744bd1c48c236027e690ab33211cc1bcf2' 
  AND token = '3FLOMpDFhM4+XJsuJsIiUTUScesTcsTSMNLBF62XOVM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}