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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd9384ea49594453c0a13363730f4f83ac442dbc521a11d1ebf9660e1b47bc81c' 
  AND token = 's/i/TVs0lbEdAf+CubejMaWFwUH5JvYItuIOoxb9vMI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}