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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '488beb9024b7faeaca40582b517b38230d63b253248c6295cac6e182bc190f52' 
  AND token = 't95bHkJT9K4QN5h2WeLZJAw72POUn3LiNB3GTnvVph4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}