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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0b5aa19d3023201fc1f719c8f4120c1319838ac168b0a36d7d098adcfa61ca0d' 
  AND token = 'REotUgyHuEFQsbEoY9pWM6BERWONYqUW6fQbA6demLY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}