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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6ee33c48db2cd8b3a9767a3904fcaf67995703dfd3b3b717d77f904849705415' 
  AND token = 'Ckfj3xFqBwXwly0CvR8UtKGoVSIVBCRbie4qRx0on00=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00057

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}