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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1543187efe16decd4d7499f3655a046431c3c837a3c82f41c19ded50daa8978c' 
  AND token = '+lqsUK6h9DzeiiBoD8jC3MRILQy1l6opXW2R+X1sGA8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}