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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '29d1c0637b78d5d5a5d5e10366a0dd971bb53a7916b1de33d1ac346746a0e8ce' 
  AND token = 'Dhb2eVZD6wR8Syptk1I5T+HLhW04FjHFq5RbMvlDiCk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}