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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e528b2bf7fdbde164e37ca39de647dae38e6012014f0d04faf377a87ee0b388a' 
  AND token = 'EQWfrLWXK3UU6Kmf15gGpsJXho2EyX4Zc6RWVUtfH+Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}