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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b978a43e0cfc6b5d20d7a2802dce6f8fd58e92bef807eb794c561bf3397610e6' 
  AND token = 'c0yMi9nC30VRKBzW7N1t9nE+eattLAcjWrot9hicYz8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}