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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5ad3309a30db8b0f3af779a0e20adabbc4cfc79e9694691fd295833da287c16d' 
  AND token = 'ogVduPsQmi3CgELFhRkxh8a21LyfWoqP5r2i+XjjIQ4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}