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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3a93a19ae2016e77e23ec5a097cfadd42280bc0a057caa51e2a8e756c6a40934' 
  AND token = 'z+TdBVwDXpaZd/TkHAJnEehHKCVshFE6vo2grcP8h7g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}