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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6458ef29d12e887992e4d2324ae7b7dca31dded98319e199454232bfd951ae2e' 
  AND token = 'BQ0+YXFuyItHDXjh0QMWjfoEQDE5yvWI+L42SDgxlA0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}