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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ee5325ebf5220a00cb23265eb120a65a2bba38fe86833926307f16c97a78e8d6' 
  AND token = 'RZYcNp/XjwU3gfyrbT4qDiI6hLR8pJMi6E7fsGzeySQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}