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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c339827079e0ed40a87d0dae97105a8f64fc687cc58020bdc4c9fbee2c839453' 
  AND token = '6B7eEJ/uNx2CT62gA0pf0TAguhQpjVOWm+92gzVnhDU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}