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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f09611bcb4d54279124314a483b8ea481aeca93a1f0982fc9189d5a3ed6e7a9e' 
  AND token = 'itzGb/aqqzdGnIAemFo/DZtS/9OoQQ4yHZGPy2VDKDw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}