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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5bc3fe1dee693c2fd3b9604a04f2fbc739aa1fbb0022b306172b6211300844a8' 
  AND token = 'IWf3VN9ev6bpPAq9Uye7zCTxRctQepVlofHJbeQH3G8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}