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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f8ae06338274e2ff7f01ae7f2b90880a44e12c1c12a3f12a79f2ac32147ec749' 
  AND token = 'x6yS5/hCHNg/NPMWvxC3ncLLj07N2MLaZjtpL2vD8Is=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}