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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '25333e2f198a763bd76570c0f6fd32ddf705afb8070db9afaba20e058cd1cc4b' 
  AND token = 'iyjvGmMU7SPVZ79p3l63c6IoGllM6i2ZAyQIq4fLJ8E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00053

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}