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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5069c9a27c27400dbeb3daaabc0c4d41bc600dcf298342eb5f74b9582cf70281' 
  AND token = '0porQN2C4hQ4URR10zOZe2UYl+TVPpHGaSMB61GPEYc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}