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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f21a21a5377f2f114281e9ae03da70e2d6c6b03c90f53a7354a494a8cbc86f50' 
  AND token = '7+hbLaXOEwibMvFogYqao2NtM6bdTbK1y6WHvbED8bg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}