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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '21b5ca401e0dc549ff6957e49911dbe96794a8cde50053fba88ed1abaaec71eb' 
  AND token = 'DIJv0WpEj8QxWeqkZiSqgvMzMuiND/nj9c28kj+Jf7U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}