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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '214497e93404e28ea1ebbe99788ef13f2a16cb763d92875b974f1c41fec7c687' 
  AND token = 'yQQNQ4shExLbPU7aYQZcD3rNbXrWUgyoZ2/BF9bIj8A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}