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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8e8ee7ba1a1c575c33b1f327072f966adf72151315336fd9151f8af94c7b2538' 
  AND token = 'CQIbKzEbJQteL4qp60o6nZctRaF6H6OjT8CGcSqNuBg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}