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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6374871bb808a5c75b2972016e8c6d8298eb11161559b92d76374b2b5f7992bf' 
  AND token = 'VCHE4EQNYSZ3+Bcr98giqxW5wMkNPoSp545Z1psbfPY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}