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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7fa57430355b80dbf51da9d0ea1e1e0e78835d014c117edf32b44959e634e28a' 
  AND token = 'Wq1utDCGuXcKq89cpD7FMbZuoCCkTGUtSPBaGKWCLAk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}